Composite score to predict hepatitis C viral infection in newborn through vertical transmission.
Faculty Mentor’s Name: Dr. Tony Wen
Phone Number: (352) 273-7562
Project Category: Translational
International Component or Travel: No
Research Project Description:
This is Mr Paul Wasuwanich’s summer research project under mentor of Dr. Robert Egerman and myself.
Objective- Retrospective analysis of cohort of pregnant women with active hepatitis C viral infection to develop a composite scoring system to predict risk for newborn infection.
Method- Retrospective chart review of cohort of pregnant women delivered at Shands hospital with known active hepatitis C viral infection and newborn follow up within the UFL health care system. Maternal demographic, social, medical, obstetrical and fetal / ultrasound factors and pregnancy / labor management will be analyzed to develop a composite scoring system to predict newborn / infant infection through vertical transmission.
Student t-test and multi- regression analysis will be conducted to develop this prediction model. The model will be tested for sensitivity and specificity.