Pediatric button cystostomy and urinary tract infections
Name:
Dr. Romano DeMarco
Email
romano.demarco@urology.ufl.edu
Phone
(352) 265-8240
Faculty Department/Division
Urology
This project is primarily:
Clinical
Research Project Description:
Review the relationship between button cystostomy and urinary tract infection in infants and young children with lower urinary tract dysfunction.
Does this project have an international component or travel?
No
Prospective Assessment of Impact of GLP1 Receptor Agonists on Risk factors, 24 Hour Urines, and Recurrence in Urinary Stone Formers
Name:
Dr. Vincent Bird
Email
vincent.bird@urology.ufl.edu
Phone
(352) 265-9052
Faculty Department/Division
Urology
This project is primarily:
Clinical
Research Project Description:
RESEARCH ABSTRACT: Urinary stone disease is common, with increasing incidence and prevalence. Stone disease, its manifestations, and treatment are associated with significant patient related morbidity, decreased quality of life, and health care cost. Urinary tract stones are highly recurrent in nature, and thus there are efforts to pursue stone prevention strategies. To date strategies, include fluids, diet modifications, supplements, and a few select medications. GLP-1 agonists are relatively recently introduced medications. Glucagon-like peptide-1 (GLP-1) agonists, also known as GLP-1 receptor agonists (GLP-1RAs), are a class of drugs that help control blood sugar and may lead to weight loss. GLP-1 agonists mimic the action of a hormone called glucagon-like peptide 1, which stimulates the body to produce more insulin when blood sugar levels rise after eating. This extra insulin helps lower blood sugar levels. Preliminary population-based studies, mostly utilizing administrative data, suggest there these new medications may be associated with decreased stone risk, however, there is a lack of high quality clinical studies, with attention paid to specific patient conditions, stone history, and actual consumption of GLP-1 agonists to better assess if these medications are potentially beneficial to urinary stone formers. We will conduct a prospective study of urinary stone formers consuming these medications to assess for the effects of GLP-1 agonists on this patient group. This project is a collaborative effort involving the University of Florida Departments of Urology and Nephrology.
Does this project have an international component or travel?
No