The effect of HIV and drugs of abuse on the blood-brain barrier
Name:
Dr. Allison Andrews
Email
andrews.allison@ufl.edu
Phone
(352) 294-5275
Faculty Department/Division
Pathology Immunology and Laboratory Medicine
This project is primarily:
Basic
Research Project Description:
Despite the use of Anti-retroviral therapy, rates of HIV-associated neurocognitive disorders (HAND) remain high in people living with HIV. A hallmark of HAND is blood-brain barrier disruption and inflammation in the CNS. Additionally, people with HIV commonly use drugs of abuse, which is known to impact HIV neuropathogenesis and contribute to neurocognitive disorders (NCI). The goal of this work is to examine the effect of various drugs of abuse on the blood-brain barrier, HIV replication and inflammation in the central nervous system (CNS).
Does this project have an international component or travel?
No